Kamil Kuca Selected Research

Hypoxia (Hypoxemia)

2/2024	HIF-1α is a "brake" in JNK-mediated activation of amyloid protein precursor and hyperphosphorylation of tau induced by T-2 toxin in BV2 cells.
9/2023	Deoxynivalenol upregulates hypoxia-inducible factor-1α to promote an "immune evasion" process by activating STAT3 signaling.
7/2023	Deoxynivalenol: Emerging Toxic Mechanisms and Control Strategies, Current and Future Perspectives.
4/2023	Mycotoxins: Emerging toxic mechanisms, and unanswered research questions.
2/2023	Mycotoxins and cellular senescence: the impact of oxidative stress, hypoxia, and immunosuppression.
1/2023	Role of hypoxia in cellular senescence.
10/2022	HIF-1α inhibits T-2 toxin-mediated "immune evasion" process by negatively regulating PD-1/PD-L1.
1/2022	Hypoxia-inducible factors: master regulators of hypoxic tumor immune escape.
1/2021	Hypoxia, oxidative stress, and immune evasion: a trinity of the trichothecenes T-2 toxin and deoxynivalenol (DON).
11/2020	The neurotoxicity of trichothecenes T-2 toxin and deoxynivalenol (DON): Current status and future perspectives.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Kamil Kuca Research Topics

Disease

80	Poisoning 11/2023 - 01/2004
58	Alzheimer Disease (Alzheimer's Disease) 05/2024 - 01/2004
39	Neoplasms (Cancer) 05/2024 - 11/2013
14	Organophosphate Poisoning 07/2020 - 08/2006
12	Hypoxia (Hypoxemia) 02/2024 - 01/2020
11	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2023 - 01/2015
9	Infections 01/2023 - 01/2010
8	Dementia (Dementias) 05/2024 - 01/2016
6	Parkinson Disease (Parkinson's Disease) 05/2024 - 01/2016
6	COVID-19 01/2022 - 01/2021
5	Pain (Aches) 04/2024 - 08/2007
5	Inflammation (Inflammations) 03/2024 - 01/2017
5	Cognitive Dysfunction 02/2024 - 01/2017
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2023 - 01/2017
5	Body Weight (Weight, Body) 10/2021 - 01/2013
5	Myasthenia Gravis 02/2016 - 11/2009
4	Vomiting 08/2023 - 01/2020
4	Nervous System Diseases (Neurological Disorders) 01/2023 - 01/2015
3	Chronic Disease (Chronic Diseases) 03/2024 - 09/2022
3	Wounds and Injuries (Trauma) 01/2021 - 04/2019
3	Breast Neoplasms (Breast Cancer) 01/2020 - 12/2017
3	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2016 - 01/2014
2	Immune System Diseases (Immune Disorders) 09/2023 - 08/2023
2	Smallpox (Variola) 01/2023 - 01/2023
2	Mpox (monkeypox) 01/2023 - 01/2023

Drug/Important Bio-Agent (IBA)

50	OximesIBA 07/2020 - 01/2004
31	AcetylcholinesteraseIBA 11/2023 - 11/2005
30	tabunIBA 01/2019 - 12/2005
20	Nerve AgentsIBA 11/2023 - 11/2005
19	asoxime chloride (H16)IBA 01/2018 - 01/2004
18	Obidoxime Chloride (Obidoxime)IBA 11/2023 - 01/2004
16	EnzymesIBA 03/2024 - 01/2004
16	Atropine FDA LinkGeneric 07/2020 - 01/2004
14	Cholinesterase Inhibitors (Anticholinesterases)IBA 03/2023 - 03/2010
13	MycotoxinsIBA 02/2024 - 01/2007
13	Tacrine (Cognex)FDA Link 01/2021 - 05/2008
11	AntioxidantsIBA 03/2024 - 12/2011
10	Trimedoxime (Trimedoxime Bromide)IBA 11/2023 - 01/2004
10	Cholinergic Agents (Cholinergics)IBA 07/2023 - 01/2004
9	Proteins (Proteins, Gene)FDA Link 11/2023 - 01/2014
9	cyclohexyl methylphosphonofluoridate (cyclosarin)IBA 06/2009 - 11/2005
8	AntidotesIBA 12/2018 - 04/2008
7	OrganophosphatesIBA 01/2023 - 01/2004
7	Amyloid (Amyloid Fibrils)IBA 01/2022 - 01/2015
6	LigandsIBA 05/2024 - 01/2016
6	Biomarkers (Surrogate Marker)IBA 04/2024 - 01/2019
6	Reactive Oxygen Species (Oxygen Radicals)IBA 10/2023 - 01/2019
6	deoxynivalenolIBA 09/2023 - 01/2020
6	T-2 Toxin (T 2 Toxin)IBA 10/2022 - 12/2017
6	pralidoxime (Protopam Chloride)FDA Link 12/2011 - 11/2005
5	VaccinesIBA 11/2023 - 01/2017
5	TrichothecenesIBA 04/2023 - 12/2017
5	Antiviral Agents (Antivirals)IBA 01/2023 - 01/2016
5	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2014
5	Amyloid beta-PeptidesIBA 03/2020 - 08/2012
5	SomanIBA 10/2010 - 02/2006
4	JNK Mitogen-Activated Protein KinasesIBA 02/2024 - 11/2019
4	Serotonin (5 Hydroxytryptamine)IBA 02/2024 - 01/2020
4	Donepezil (Aricept)FDA LinkGeneric 09/2023 - 12/2018
4	trichotheceneIBA 08/2023 - 12/2017
4	benzothiazoleIBA 01/2021 - 01/2015
4	Therapeutic UsesIBA 01/2019 - 05/2007
4	Cholinesterases (Cholinesterase)IBA 01/2017 - 08/2007
4	Phosphotransferases (Kinase)IBA 01/2016 - 01/2014
4	Cholinergic Antagonists (Anticholinergics)IBA 10/2008 - 11/2005
3	Sirolimus (Rapamycin)FDA Link 12/2023 - 03/2021
3	PesticidesIBA 11/2023 - 12/2009
3	MicroRNAs (MicroRNA)IBA 09/2023 - 01/2019
3	CurcuminIBA 09/2023 - 01/2023
3	neuropeptide Y2 receptorIBA 08/2023 - 01/2020
3	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 08/2023 - 01/2020
3	Granisetron (Kytril)FDA LinkGeneric 08/2023 - 01/2020
3	CopperIBA 01/2023 - 01/2016
3	CytokinesIBA 01/2022 - 08/2018
3	GoldIBA 01/2021 - 10/2016
3	Oxidoreductases (Dehydrogenase)IBA 03/2020 - 01/2017
3	diacetoxyscirpenolIBA 01/2020 - 12/2017
3	SaltsIBA 12/2019 - 01/2013
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2019 - 01/2015
3	Memantine (Namenda)FDA Link 01/2019 - 06/2014
3	Diazepam (Valium)FDA LinkGeneric 09/2018 - 01/2011
3	SarinIBA 01/2018 - 07/2005
3	Malathion (Karbofos)FDA LinkGeneric 12/2011 - 01/2008
3	CarbamatesIBA 01/2011 - 01/2004
3	Paraoxon (E600)IBA 09/2010 - 11/2007
3	Acetylcholine (Acetylcholine Chloride)FDA Link 03/2010 - 11/2005
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2024 - 01/2021
2	diazonaphthalenedisulfonic acid (NDS)IBA 05/2024 - 01/2022
2	Glutathione (Reduced Glutathione)IBA 03/2024 - 01/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2024 - 01/2022
2	PhytochemicalsIBA 02/2024 - 09/2023
2	Analgesics (Analgesic Drugs)IBA 02/2024 - 04/2019
2	Peptides (Polypeptides)IBA 11/2023 - 01/2015
2	Peptide YYIBA 08/2023 - 01/2020
2	AflatoxinsIBA 04/2023 - 10/2021
2	PoisonsIBA 01/2023 - 01/2019
2	Messenger RNA (mRNA)IBA 01/2023 - 01/2023

Therapy/Procedure

37	Therapeutics 05/2024 - 02/2006
4	Drug Therapy (Chemotherapy) 01/2024 - 01/2019
3	Immunotherapy 05/2024 - 01/2021